Residue Interaction Network Service

Protein is a kind of common biological macromolecule, which plays an important role in life activities. It is very necessary to study protein structure, evolution or key residues in protein from a global perspective. The protein molecule is transformed into an amino acid interaction network with amino acids as nodes and their interactions as edges. The complex network theory is used to analyze, which provides a new perspective for the study of protein-related issues.

Construction of residue interaction network

Residue interaction

The three-dimensional structure of a protein can also be transformed into an undirected network, with the amino acids constituting the protein as the nodes and the interaction between amino acids as the edges. This kind of network is called amino acid interaction network (Amino Acids Network, AAN), residue interaction network (Residues Interaction Network, RIN) or protein structure network ((Protein Structure Network, PSN). Here, we named this type of network after amino acid interaction network in order to distinguish it from protein interaction network. Studying protein from the perspective of network can better study its topological properties and the overall connectivity of each component in the protein molecule.

Overall solutions

MedAI has many years of experience in the research of biological complex networks. In the past years, we have worked with many research institutes and pharmaceutical companies to solve problems related to complex networks for customers. We can provide you with the following services but not limited to:

Residue interaction network
  • MedAI uses RINs analysis to provide you with professional complex analysis of proteins and their complexes.
  • MedAI can estimate their interdependence for you, and predict the different properties and functions of individual residues and entire proteins.
  • MedAI can analyze the chemical and physical properties of bases and the energy of their interaction through the construction of RIN.
  • MedAI can study the structure and function of proteins through RINs, and can be applied to drug design in a variety of ways.

Services items

Project name Complex network analysis service
Our services MedAI uses RINs analysis to provide you with professional complex analysis of proteins and their complexes, predict the different properties and functions of individual residues and the entire protein, and analyze the chemical and physical properties of bases and the energy of their interaction through the construction of RIN . In addition, MedAI can also provide you with analysis of the nature of the network.
Cycle Depends on the time you need to simulate and the time required for the system to reach equilibrium.
Product delivery mode The simulation results provide you with the raw data and analysis results of molecular dynamics.
Price Inquiry

MedAI provides corresponding professional amino acid network services. Our residue interaction service has proven to be very useful for understanding the biochemical basis of physiological events at different stages of drug development (even in different fields such as materials science). The MedAI team has worked in this field for more than a decade and published his findings in top scientific journals. If you need network analysis services, please feel free to contact us.

Services

Online Inquiry

Please submit a detailed description of your project. We will provide you with a customized project plan to meet your research requests. You can also send emails directly to inquiry@protheragen.com for inquiries.

Verification code

Copyright © 2021 Protheragen Inc. All Rights Reserved.